|
Date |
Name |
Title |
Volume |
Trade Price |
Holding Change |
|
6/18/2013
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-16,630
|
$5.46
|
-0.52%
|
|
6/18/2013
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-313
|
$5.46
|
-0.52%
|
|
6/17/2013
|
DP VI Associates, L.P.
|
Substantial Shareholder
|
-959
|
$5.40
|
-2.41%
|
|
6/17/2013
|
Domain Partners VI, L.P.
|
Substantial Shareholder
|
-87,812
|
$5.40
|
-2.17%
|
|
6/17/2013
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-372
|
$5.42
|
-0.61%
|
|
6/17/2013
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-19,748
|
$5.42
|
-0.61%
|
|
6/14/2013
|
DP VI Associates, L.P.
|
Substantial Shareholder
|
-425
|
$5.03
|
-1.06%
|
|
6/14/2013
|
Domain Partners VI, L.P.
|
Substantial Shareholder
|
-38,897
|
$5.03
|
-0.95%
|
|
6/11/2013
|
Domain Partners VI, L.P.
|
Substantial Shareholder
|
-5,337
|
$5.00
|
-0.13%
|
|
6/11/2013
|
DP VI Associates, L.P.
|
Substantial Shareholder
|
-59
|
$5.00
|
-0.15%
|
|
5/17/2013
|
Holland David
|
SVP of Sales & Marketing
|
-30,000
|
$4.13
|
-23.37%
|
|
5/16/2013
|
Domain Partners VI, L.P.
|
Substantial Shareholder
|
-21,276
|
$4.50
|
-0.52%
|
|
5/16/2013
|
DP VI Associates, L.P.
|
Substantial Shareholder
|
-232
|
$4.50
|
-0.57%
|
|
5/15/2013
|
DP VI Associates, L.P.
|
Substantial Shareholder
|
-251
|
$4.70
|
-0.62%
|
|
5/15/2013
|
Domain Partners VI, L.P.
|
Substantial Shareholder
|
-22,966
|
$4.70
|
-0.56%
|
|
12/13/2012
|
EISWIRTH RICHARD S JR
|
COO and CFO
|
5,000
|
$1.44
|
48.55%
|
|
12/13/2012
|
Pizzo Peter J. III
|
Director
|
5,000
|
$1.44
|
200.00%
|
|
12/3/2012
|
Myers C. Daniel
|
President and CEO
|
-7,700
|
$1.95
|
-6.13%
|
|
11/1/2012
|
Myers C. Daniel
|
President and CEO
|
-5,950
|
$2.52
|
-4.56%
|
|
10/1/2012
|
Myers C. Daniel
|
President and CEO
|
-5,900
|
$2.52
|
-4.07%
|
|
9/4/2012
|
Myers C. Daniel
|
President and CEO
|
-6,350
|
$2.36
|
-4.20%
|
|
8/13/2012
|
EISWIRTH RICHARD S JR
|
COO and CFO
|
-4,463
|
$2.28
|
-30.23%
|
|
8/13/2012
|
Green Kenneth
|
SVP & Chief Science Officer
|
-3,612
|
$2.28
|
-32.45%
|
|
8/13/2012
|
Holland David
|
SVP of Sales & Marketing
|
-3,630
|
$2.28
|
-2.81%
|
|
8/13/2012
|
Myers C. Daniel
|
President and CEO
|
-6,388
|
$2.28
|
-3.88%
|
|
8/13/2012
|
Myers C. Daniel
|
President and CEO
|
-6,745
|
$2.22
|
-4.27%
|
|
11/15/2011
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-294,822
|
$1.47
|
-8.32%
|
|
11/15/2011
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-5,203
|
$1.47
|
-7.91%
|
|
11/14/2011
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-2,559
|
$1.77
|
-3.75%
|
|
11/14/2011
|
Polaris Venture Management Co IV LLC
|
Senior Executive Officer
|
-167,747
|
$1.77
|
-4.52%
|
|
8/19/2011
|
Caballa Susan
|
SEE REMARKS
|
3,000
|
$7.15
|
5.53%
|
|
8/19/2011
|
Caballa Susan
|
SEE REMARKS
|
3,000
|
$7.15
|
5.53%
|
|
6/28/2011
|
Roberts Calvin W.
|
Director
|
4,412
|
$2.04
|
1.98%
|
|
6/7/2011
|
Green Kenneth
|
SVP & Chief Scientific Officer
|
7,941
|
$1.33
|
56.61%
|
|
6/7/2011
|
Green Kenneth
|
SVP & Chief Scientific Officer
|
-21,969
|
$8.00
|
-100.00%
|
|
6/2/2011
|
VITULLO NICOLE
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
6/2/2011
|
TREU JESSE I
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
6/2/2011
|
SCHOEMAKER KATHLEEN K
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
6/2/2011
|
DP VI Associates, L.P.
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
6/2/2011
|
BLAIR JAMES C
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
6/2/2011
|
DOVEY BRIAN H
|
TenPercent
|
-6,914
|
$8.04
|
-14.49%
|
|
3/15/2011
|
Myers C. Daniel
|
President and CEO
|
-45,523
|
$7.06
|
-23.37%
|
|
3/10/2011
|
Myers C. Daniel
|
President and CEO
|
55,147
|
$1.33
|
36.95%
|
|
3/10/2011
|
Myers C. Daniel
|
President and CEO
|
-9,624
|
$7.66
|
-4.71%
|
|
3/10/2011
|
Roberts Calvin W.
|
Director
|
10,000
|
$7.75
|
98.04%
|
|
2/25/2011
|
Roberts Calvin W.
|
Director
|
7,600
|
$7.87
|
292.31%
|