|
Date |
Name |
Title |
Volume |
Trade Price |
Holding Change |
|
2/28/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
23,495
|
$25.14
|
0.46%
|
|
2/28/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
515
|
$25.04
|
0.37%
|
|
2/28/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
649
|
$25.14
|
0.47%
|
|
2/25/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
356
|
$23.89
|
0.26%
|
|
2/25/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
13,986
|
$24.23
|
0.28%
|
|
2/25/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
12,897
|
$23.89
|
0.25%
|
|
2/25/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
8,195
|
$23.95
|
0.16%
|
|
2/25/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
386
|
$24.23
|
0.28%
|
|
2/25/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
226
|
$23.95
|
0.16%
|
|
2/24/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
48,224
|
$23.43
|
0.97%
|
|
2/24/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
24,318
|
$23.47
|
0.48%
|
|
2/24/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
1,331
|
$23.43
|
0.98%
|
|
2/24/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
671
|
$23.47
|
0.49%
|
|
2/24/2011
|
Shak Steven
|
Chief Medical Officer
|
5,000
|
$9.39
|
1.27%
|
|
2/24/2011
|
Shak Steven
|
Chief Medical Officer
|
-5,000
|
$23.27
|
-1.26%
|
|
2/23/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
33,009
|
$22.88
|
0.67%
|
|
2/23/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
911
|
$22.88
|
0.68%
|
|
2/23/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
2,393
|
$22.87
|
0.05%
|
|
2/23/2011
|
Baker Brothers Life Sciences Capital (GP), LLC
|
Senior Executive Officer
|
15,333
|
$22.88
|
0.31%
|
|
2/23/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
423
|
$22.88
|
0.31%
|
|
2/23/2011
|
14159 capital (GP), LLC
|
Senior Executive Officer
|
66
|
$22.87
|
0.05%
|
|
2/15/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$22.65
|
-1.33%
|
|
2/15/2011
|
Schorno Dean L
|
CFO
|
-1,000
|
$22.51
|
-4.18%
|
|
2/15/2011
|
Popovits Kimberly J
|
President and CEO
|
4,000
|
$9.39
|
1.35%
|
|
2/14/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$22.39
|
-1.33%
|
|
2/14/2011
|
Popovits Kimberly J
|
President and CEO
|
4,000
|
$9.39
|
1.35%
|
|
2/11/2011
|
Scott Randal W
|
Executive Chairman
|
-10,000
|
$22.28
|
-0.62%
|
|
2/10/2011
|
Scott Randal W
|
Executive Chairman
|
-10,000
|
$22.12
|
-0.62%
|
|
2/8/2011
|
Cole G Bradley
|
COO
|
-2,500
|
$23.24
|
-24.39%
|
|
2/8/2011
|
Cole G Bradley
|
COO
|
2,500
|
$1.33
|
32.26%
|
|
1/18/2011
|
Popovits Kimberly J
|
President and CEO
|
4,000
|
$2.88
|
1.39%
|
|
1/18/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$21.19
|
-1.37%
|
|
1/18/2011
|
Popovits Kimberly J
|
President and CEO
|
1,347
|
$2.88
|
0.47%
|
|
1/18/2011
|
Popovits Kimberly J
|
President and CEO
|
2,653
|
$9.39
|
0.92%
|
|
1/18/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$21.19
|
-1.37%
|
|
1/14/2011
|
Popovits Kimberly J
|
President and CEO
|
4,000
|
$2.88
|
1.39%
|
|
1/14/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$21.11
|
-1.37%
|
|
1/14/2011
|
Popovits Kimberly J
|
President and CEO
|
-4,000
|
$21.11
|
-1.37%
|
|
1/14/2011
|
Popovits Kimberly J
|
President and CEO
|
4,000
|
$2.88
|
1.39%
|
|
1/13/2011
|
Schorno Dean L
|
CFO
|
1,276
|
$2.88
|
6.38%
|
|
1/13/2011
|
Schorno Dean L
|
CFO
|
-1,276
|
$21.06
|
-6.00%
|
|
1/11/2011
|
Scott Randal W
|
Executive Chairman
|
-10,000
|
$21.71
|
-0.61%
|
|
1/10/2011
|
Scott Randal W
|
Executive Chairman
|
-10,000
|
$21.75
|
-0.61%
|
|
1/6/2011
|
Cole G Bradley
|
COO
|
5,000
|
$1.33
|
500.00%
|
|
1/6/2011
|
Cole G Bradley
|
COO
|
-5,000
|
$22.13
|
-83.33%
|